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Jan 11, 2022 Victoria NISTREANU, Alina LARION
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Introduction.  Airport territories are large, containing a high variety of biotopes, mostly open type, and are relatively protected against intense human activity, thus creating favorable conditions for many mammal species that serve as trophic source for many bird species. Material and methods . The studies were performed during 2012-2014 on the territory of Chisinau airport and within the adjacent ecosystems. The mammals were recorded by direct observations, based on traces and trophic...
Topics: Chisinau airport, mammals, rodents, abundance, fox, trophic connections
Introduction.  Deterioration of left ventricular (LV) parameters in Diabetes Mellitus (DM) can occur in the absence of other heart problems. An association between glycosylated hemoglobin (HbA1c) and changes of the LV parameters in DM has been reported. However, data regarding this association model in children with Type 1 Diabetes Mellitus (T1DM) are limited. The purpose of the work was to investigate the association between HbA1c and the LV parameters in pediatric patients. Material and...
Topics: children, Diabetes Mellitus, left ventricle, glycosylated hemoglobin.
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Jan 11, 2022 Vyacheslav DANCHUK, Svitlana MIDYK, Valerii USHKALOV, Olga IAKUBCHAK, Ihor HRYSHCHUK, Liliana DAVYDOVSKA
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Introduction.  There are several important aspects requiring a control of fatty acid composition in drinking milk distributed across the retail stores: milk is one of the main consumer products; fatty acids are the main energy substrates, involved in the synthesis of cellular structural components, whereas their interaction might impact the intensity of body growth and development; the fatty acid composition of milk varies depending on the diet and the animal's specific physiological state; in...
Topics: fatty acids, drinking cow's milk.
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Jan 11, 2022 Hanan AQEEHAL, Ahmed ALARBI, Haytham MANEEA, Mahmud BENMANSUR, Abdelhadi ELTURKI, Anud ZAABIA, Rachid BENTOUTA, Jebril GEBRIL
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Introduction.  To stop SARS-CoV-2 from spreading, it's crucial to have a solid understanding of the baseline characteristics of demographic variables, clinical symptoms, and comorbidity so that quarantining and testing protocols can be developed. Material and methods.  A retrospective study was conducted on COVID-19 Laboratory confirmed cases. Data were collected by using kobo toolbox, demographic variables, clinical symptoms, and Comorbidity was considered. Yates-corrected chi2 tests and...
Topics: SARS-CoV-2, comorbidity, clinical symptoms, Libya.
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Introduction . HAIs present a major public health problem with an impact on morbidity, mortality and quality of life. The objective of the study was to highlight the problem of HAIs and AM use, identification of risk factors and raising awareness of the phenomenon. Material and methods . The methodology of the PPS was patient-based, developed based on ECDC Protocol 5.3/2016. The study was accomplished in 2018. The sample of the PPS included 67 hospitals, 546 wards and 10594 patients. Results ....
Topics: point prevalence survey, healthcare-associated infections, antimicrobial use.
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Introduction.  Currently, neurodegenerative diseases (ND) are the fourth leading cause of death worldwide that pose a great challenge in the development of tools for early diagnosis. Thus, advances in science seek sensitive and selective detection systems and this manuscript will highlight the importance of nanotechnology. Material and methods.  A literature review was conducted on the representative findings of NPs technologies in neurodegenerative diseases. Articles written in both English...
Topics: nanoparticles, gold, magnetite, amyloid proteins, neurodegenerative diseases.
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Jan 11, 2022 Angela PELTEC, Murad ALNABGHALIE
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Introduction.  The prevalence of nonalcoholic fatty liver disease (NAFLD) in western countries is increasing rapidly and is considered as component of metabolic syndrome. Endothelial dysfunction is a pathophysiological problem of cardiovascular disease. NAFLD, as a component of metabolic syndrome, is associated with endothelial dysfunction. Material and methods.   PubMed database  was used in order to review and select articles according to the keywords. A total of 216 articles matching...
Topics: endothelial dysfunction, nonalcoholic fatty liver disease, nitric oxide.
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Oct 30, 2021 Igor PETCU, Nicolae STARCIUC
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Introduction.   Currently, various biologically active substances, preferably of biological and not synthetic origin, with having a growth stimulating effect, are frequently used as food additives in the poultry industry . Some of these substances with a stimulating effect on the growth of chickens are represented by the biomass obtained from apathogenic strains of Streptomycetes. Material and methods.  The investigations were conduvted within the ILR “Avicola Sărătenii-Vech” v....
Topics: chickens, biomass of Streptomycetes, body weight, resistance.
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Oct 30, 2021 Valentina MARINESCU, Anda Anca RODIDEAL
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Introduction.  The unexpected situations (lockdown, online school, social distancing)   introduced from March 2020 to stop the spread of COVID-19 in most countries worldwide, have affected every citizen. Currently, after more than a year and a half, one of the most affected categories are the children. There is growing concern among researchers about the pandemic impact on the physical, mental development and health of children. Material and methods.  A quantitative research was conducted...
Topics: COVID19 pandemic restrictions, online school, children physical and psychical/mental health.
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Oct 30, 2021 Maxim SIRBU, Nicolae STARCIUC
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Introduction.  Rabies is one of the most dangerous zoonoses in the world with a lethality rate around 100% of infected animals. The main factor in rabies’ control is the prophylactic immunization of domestic and wild carnivores. Material and methods.  As a research material  for this manuscript , a number of rabies cases in wildlife over the last 5 years was studied, as well as some data from the national program regarding the vaccination of wildlife animals in the Republic of Moldova....
Topics: rabies, foxes, virus, vaccination, incidence.
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Oct 30, 2021 Ludmila BIRCA, Diana SPATARU, Stela CORNILOVA, Viorica HEMEI, Olesea AIOANI
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Introduction.  The population of all ages is susceptible to SARS-CoV-2 virus. It is important to determine the role of the child in COVID-19 cases maintenance and spreading. Some research showed that most COVID-19 cases in children were associated with their families. Material and methods.  The descriptive study is carried out on the basis of family outbreaks epidemiological peculiarities evaluation, concerning the age of the children, the onset of the disease, communities living environment....
Topics: COVID-19 infection, children, family outbreaks, sources of infection.
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Oct 30, 2021 Adriana ALBU, Irina Mihaela ABDULAN, Catalin Dragos GHICA
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Introduction.  Eating habits are formed in the first years of life and sometimes persist throughout lifetime. It is necessary to develop coherent nutritional educational programs to guide adolescents towards a healthy diet. Material and methods.  The study was conducted on a group of 194 students from the ninth and the twelfth grade from Dimitrie Cantemir High School in Iasi. These young people were evaluated for their physical development with the help of body mass index and eating habits....
Topics: physical development, eating habits, high school students.
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Oct 30, 2021 Olga PENINA
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Introduction . Cancer is the second cause-of-death mortality pattern in the Republic of Moldova. The study of both cancer mortality by age and its detailed causes is an important tool for evidence-based public health policy. The study aims at comparing recent changes in cancer mortality with long-term trends, depending on specific causes and age. Material and methods . This study was carried out on the reconstructed 1965-2018 death time series, according to the 10th revision of the...
Topics: mortality, cancer, Republic of Moldova
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Oct 30, 2021 Erika Yohanna BEDOYA CARDONA, Ioana POPA, Anna MORANDI, Cristina MONTOMOLI
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Introduction.  As part of the holistic concept of health, mental health can be focused on prevention of contagion and coping with the disease and its consequences in the context of the current COVID-19 pandemic. The present study describes, compares, and analyzes the association of the impact of the event, perceived stress, coping strategies, emotional regulation, and sociodemographic characteristics during the quarantine in various countries. Material and methods.  This research is a...
Topics: mental health, COVID-19 quarantine, pandemic.
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Oct 30, 2021 Maria-Victoria RACU, Ion Romulus SCOREI, Iurie PINZARU
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Introduction.  Boron is a trace mineral that is supposed to be essential for human health. Organic plant based boron compounds are highly bioavailable for humans and can positively influence minerals such as calcium, phosphorus, magnesium and act in synergy with vitamin D, which are beneficial for osteoarticular health. Material and methods.  We made an analysis of 126 bibliographic sources and mapped the Republic of Moldova to the content of boron in deep water and to the adults’...
Topics: osteoarticular diseases, boron, boron compounds.
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Introduction.  The interest in Global Health (HG) as an academic discipline has increased in the last decade. The Rouen School of Medicine is one of the first to offer a GH curriculum in France. The objective was to identify the characteristics and profile of students involved in a GH curriculum.  Material and methods.  In 2016 and 2017, a cross-sectional study was conducted, including enrolled in the GH course: 3rd and 4th year in medicine, midwifes studies and pharmacy. Based on...
Topics: global health, school of medicine, training, multidisciplinary, public health.
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Oct 30, 2021 Aurelia ABABII
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Introduction.  Radon is a chemical element of increased interest to the scientific community due to its implications in the etiology of bronchopulmonary cancer. Pollution of indoor air with radon causes serious effects on health, due to alpha radiation emitted following the process of disintegration into isotopes that together with dust particles, dust enters the alveolar level. Material and methods.  This study was based on the analysis of bibliographic sources within the PubMed and Google...
Topics: residential radon, lung cancer, radon-tobacco synergism.
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Oct 30, 2021 Svetlana COCIU, Olga IONCU, Camelia CAZACU-STRATU , Serghei CEBANU, Cara HAMANN
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Introduction.   Road traffic injuries are a major public health problem, ranking 8 th  in the leading causes of death and are forecasted to rank 5 th  by 2030 worldwide. Children, pedestrians, cyclists and the elderly remain among those most at risk of road traffic injuries. Material and methods.  A specialized literature search was conducted within the main international databases, including: PubMed/MEDLINE, Google Scholar, and Research Gate, using a set of inclusion criteria. Data from...
Topics: motor vehicle injuries, risk factors, car accident, prevention.
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Oct 30, 2021 Irina Mihaela MATRAN, Daniela Lucia MUNTEAN, Cristina NICULAS, Roxana Maria MARTIN-HADMAS, Monica TARCEA
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Introduction .  The advertising of food supplements on various media channels or in specialty stores with natural products and other places, as well as the lack of informative and educational programs for the population upon side effects and the interaction of food supplements with food and drugs, have led to the development of uncontrolled marketing of these products. Material and methods . PubMed, ResearchGate and EUR-Lex databases were analyzed during 2015-2021, based on search criteria...
Topics: nutrivigilență, algoritmi, suplimente alimentare, efecte secundare.
Introduction. Protection measurements should be paid attention so that the regions affected to a great extent gain time for medical care and medical facilities can cope with increasing intensive care cases. The purpose of this study was to investigate the change in the rate of behaviours of people related to going out and wearing a mask during the pandemic in Turkey. Material and methods. This observational study investigated people’s behaviours of going out and mask-wearing in the province...
Topics: mask, containment measures, Covid-19, Turkey, lockdown.
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Jul 14, 2021 Veaceslav GUTU
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5-10
Topics: hepatitis E, seroprevalence, routes of transmision, hepatitis E virus, genotype, high-risk...
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Jul 14, 2021 Diana SPATARU, Angela PARASCHIV, Ion BERDEU
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11-18
Topics: Clostridium difficile, epidemiology of Clostridium difficile, Clostridium difficile surveillance
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Jul 14, 2021 Adela TURCANU, Suhaib TAHIR WANI
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19-26
Topics: HDV, HBV, CIRRHOSIS, HCC, IVUD (intravenous drug users)
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Jul 14, 2021 Ion BERDEU, Diana SPATARU, Angela PARASCHIV
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27-35
Topics: vaccination, new technologies, viral vectors
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Jul 14, 2021 Viorel PRISACARI, Nicoleta ANDRONACHI
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36-41
Topics: Acinetobacter baumannii nosocomial infections, antibiotic resistance
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Jul 14, 2021 Ala DONOS, Tatiana ALSALIEM, Constantin SPINU, Ninel REVENCO, Valentin TUREA, Ion MIHU, Radu COJOCARU, Stela GHEORGHITA, Igor SPINU, Albina-Mihaela ILIEV, Luminita SUVEICA
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42-50
Topics: diarrhea, rotavirus, children, infants, vaccine
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Jul 14, 2021 Viorel PRISACARI, Diana BUGA, Ion BERDEU
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51-57
Topics: trophic ulcers, methicillin-resistant Staphylococcus, methicillin-sensitive Staphylococcus, risk...
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Jul 14, 2021 Constantin SPÎNU, Svetlana CEBOTARI, Octavian SAJIN, Igor SPÎNU, Ala DONOS, Ana VOLNEANSCHI, Igor GOSTEV, Iurie DOPIRA
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58-64
Topics: COVID-19 treatment, plasma donors, anti SARS-CoV-2, IgG class antibodies
65-74
Topics: hepаtitis B virus, hemodiаlysis pаtients, HBsАg, аnti-HBs, аnti-HBcor
75-82
Topics: COVID-19, SARS-CoV-2, infectiousness rate, incidence, prevalence, case incidence, ratio, medical...
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83-92
Topics: chronic hepatitis, liver cirrhosis, primary liver cancer, prevalence, morbidity, risk factors
93-101
Topics: acute flaccid paralysis, surveillance, polio strains
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Jul 14, 2021 Olga JUNCU, Nicolae STARCIUC, Natalia OSADCI, Tatiana ANTOHII
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102-107
Topics: Salmonella, poultry, meat, egg, serotype
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Jul 3, 2021 Valerii USHKALOV, Vyacheslav DANCHUK, Artem USHKALOV, Aidyn SALMANOV, Yuriy VISHOVAN, Sergiy BOIANOVSKIY, Sergiy TERESHCHENKO, Liliana DAVYDOVSKA
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48-54
Topics: Escherichia coli, strains, microorganisms, raw milk, antibiotic resistance, susceptibility.
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Jul 3, 2021 Igor PETCU
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Introduction.  The breeding of domestic poultry is an important source to soupplement the human needs in animal proteins with a high biological value. Therefore, knowledge and guidance of the factors that influence poultry production is a guarantee of increasing these productions, both in terms of quantity and quality. Material and methods.  The investigation was aimed to administer the 0.05% and 0.1% streptomyces biomass in the recipe of combined fodder, intended for the feeding of young...
Topics: streptomyces biomass, young poultry, gross weight gain, specific consumption.
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Jul 3, 2021 Nina VRYNCHANU, Yurii KOROTKIJ, Nataliia HRYNCHUK, Irina BOIKO, Elena SMERTENKO, Larisa BONDARENKO
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Introduction.  The microbial biofilm-forming ability is one of the major aspects of the emerging issue of antibiotic resistance, which makes them tolerant to antibiotics and host defense systems and other external stresses, thus contributing to persistent chronic infections. A series of relevant studies confirmed the high efficiency of aminopropanol derivatives as potential antibacterial and antifungal agents. This present study was aimed to evaluate the antimicrobial activity of new...
Topics: aminopropanol derivatives, antimicrobial activity, bacteria, biofilm.
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Jul 3, 2021 Olga POSTOLACHI, Inna RASTIMESINA, Valentina JOSAN
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Introduction . In recent years, due to wide applications of nanotechnologies in various fields, the safety of nanomaterials has become a pressing issue.  Fullerene C 60  is not an exception. Research on the activity of microorganisms and their interaction with nanoparticles is of major importance, both for microorganisms and for the ecosystem as a whole. Material and methods.   Fullerene C 60 powder was purchased from Sigma-Aldrich. The object of study was R. rhodochrous CNMN-Ac-05 strain. ...
Topics: fullerene C60, rhodococci, viability, phenotypic heterogeneity.
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Jul 3, 2021 Elena CIOBANU, Catalina CROITORU, Virginia SALARU, Marie Pierre TAVOLACCI, Joël LADNER
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10-18
Topics: students, physical activity, somatometric indices.
19-26
Topics: mask, containment measures, Covid-19, Turkey, lockdown.
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Jul 3, 2021 Maria MELNIC, Olesea GLIGA, Dumitru ERHAN, Stefan RUSU, Elena IORDOSOPOL
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39-47
Topics: potato, nematodes, arthropods, nematophagous, phytophagous., bacteria, fungi, and arthropods, which...
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55-60
Topics: antimicrobial activity, antioxidant-enzyme activity, chemical compounds, CT, SOD.
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Jul 3, 2021 Doina TURCAN, Lucia ANDRIES, Alexandr DORIF, Victoria SACARA
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61-66
Topics: Wiskott Aldrich syndrome, Xlinked thrombocytopenia, immunodeficiency.
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Jan 4, 2021 Eugen TCACIUC, Mariana PODUREAN, Olga SCHIOPU, Aurel BATRINAC, Angela SELIVANOV, Dumitru COLOMAN
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Abstract Introduction .  Paracetamol is the most commonly used drug across Western Europe and North America. There is no such trend of using Paracetamol in the Republic of Moldova, thus overdose cases are extremely rare. The mechanisms leading to overdose episodes might induce hepatotoxicity. Clinical case.  This present article reports a case of acute liver failure induced by Paracetamol overdose. A 46-year-old man presented to the Medpark International Hospital. He was administered...
Topics: Paracetamol, overdose, N-acetyl-cysteine, hepatotoxicity, acute liver failure
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Jan 4, 2021 Mircea BOLOGA, Elvira VRABIE, Irina PALADII, Olga ILIASENCO, Tatiana STEPURINA, Valeria VRABIE, Albert POLICARPOV, Catalina SPRINCEAN
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Abstract Introduction.  Whey is a by-product and an excellent source of proteins that is rather aggressive due to a large amount of organic substances it contains. The electro-activation of whey applied in the experiments is a wasteless method that allows the va-lorification of all whey components. β-lactoglobulin (β-Lg) makes up 50% of the whey proteins and 12% of the total protein content in milk. Material and methods.  The recovery of β-Lg in protein-mineral concentrates (PMC) by...
Topics: whey, protein-mineral concentrates, β-lactoglobulin, electroactivation
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Abstract Introduction .  The genus Lepraria includes diffuse or indefinitely delimited species, always sterile, Lendemer (1) naming it „the most unusual member of the sterile lichen crusts”. According to  Tonsberg (2) , the leprarioid state appeared as an adaptation to a substrate characterized by dry surfaces, in sites with high humidity and low illumination. The thallus is leprose with an entirely sorediate surface. The lack of fruiting bodies has made the lichens from this group among...
Topics: lichenized fungi, Lepraria, key, biodiversity
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Jan 4, 2021 Nataliia HRYNCHUK, Tetiana BUKHTIAROVA, Daria DUDIKOVA, Nina VRYNCHANU, Vira NEDASHKIVSKA, Iryna BOIKO, Yurii KOROTKYI, Larisa BONDARENKO
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Abstract Introduction.  The present study assessed  Pseudomonas aeruginosa surface characteristics, motility and adhesion properties under the influence of 1-[4-(1,1,3,3-tetra methyl butyl) phenoxy]-3-(N-benzyl hexa methylene iminium)-2-propanol chloride (KVM-194). Material and methods.  The clinical strain P. aeruginosa 449 was used in the study. The cell surface hydrophobicity (CSH) was evaluated by adhesion to solvent (MATS test). Swimming, swarming and twitching motility of P....
Topics: Pseudomonas aeruginosa, hydrophobicity, motility, adhesion, biofilms
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Jan 4, 2021 Ninel REVENCO, Anatol LITOVCENCO, Svetlana HADJIU, Cornelia CALCII, Rodica EREMCIUC, Olga GAIDARJI
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Abstract Introduction.  Hip pain is common in childhood. The main dilemma is to differentiate between benign conditions and those causing significant morbidity and mortality. Material and methods.  A clinical case report of a toddler presenting with Musculoskeletal (MSK) mask due to a brain tumor. Results.  A 2-year-old boy presented to the ER complaining of hip pain, muscle weakness, and limping.  The neurologic exam showed no abnormalities. At the 3 rd  day of admission, patient...
Topics: astrocytoma, brain tumor, musculoskeletal mask, children
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Abstract Introduction.  Drinking water includes a multitude of natural elements, with a strong connection between them, which through the dynamics of their modification in many cases influence the health of the population. Material and methods.  The quality of drinking water from the Prut river ecosystem was studied (water from aqueducts fed from the river, water from artesian wells, water from adjacent wells), health status of the population from riparian localities (Lipcani, Ungheni and...
Topics: sanitary-chemical indicators of water, population morbidity, correlation, risk
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Jan 4, 2021 Rodica STURZA, Valentin GUDUMAC, Olga DESEATNICOVA, Aliona GHENDOV-MOSANU
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Abstract Introduction.  One of the major problems characterizing the nutritional status is the iron deficiency, which leads to decreased immunity, increased incidence of infectious diseases and anemia. Obviously, only well-thought-out corrections can solve these disorders.  Material and methods  In order to know the influence of the method of manufacture for iron-fortified products on the iron level, a series of in vivo research was carried out, on a batch of 21 white rats, Wistar line,...
Topics: iron anemia, rats, in vivo research, fortified bread, lactic acid fermentation peripheral blood...
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Jan 4, 2021 Arjana TAMBIC ANDRASEVIC, Ivana ANTAL ANTUNOVIC
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Abstract Introduction . Gram-negative bacilli belonging to the order Enterobacterales are normal inhabitants of the human gut, which also are the most common causative agents of both nosocomial and community acquired infections in patients of all ages.  Although not even a century has passed since Fleming's discovery of penicillin, the scientists have been alarmed by the fact that the "last resort antibiotics" viz. carbapenems have been compromised. Material and methods.  The...
Topics: carbapenem-resistant Klebsiella, pneumoniae, carbapenem resistant, Enterobaacterales, carbapenems,...
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Jan 4, 2021 Ninel REVENCO, Lucia ANDRIES, Victoria SACARA, Alexandr DORIF, Doina BARBA, Rodica EREMCIUC, Olga GAIDARJI
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Abstract Introduction . Autoinflammatory diseases are a group of genetically inherited disorders and familial Mediterranean fever is the most common of this group. It is rare in other than Middle East populations. Clinical manifestations of FMF are attacks of fever usually shorter than 24 hours, associated with arthritis, pleuritic chest pain, and abdominal pain. Case presentation .  A 15-year-old female patient was included in the study. She complained of recurrent episodes of fever...
Topics: autoinflammatory diseases, familial Mediterranean fever, children
Abstract Introduction . The rapid development of information technologies has provided challenges and opportunities for effective documentation of plant genetic resources (PGR). Access to information on PGR is essential for their conservation and sustainable utilization. Material and methods.  Information System on PGR in Republic of Moldova – ReGen was created to manage the data on PGR conservation at the national level and represents unified system that includes three basic functional...
Topics: conservation, gene bank, plant genetic resources, information system, documentation
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Abstract Introduction.  The major and most common mechanisms for almost all antimicrobial substances is the induction of oxidative stress responses within the pathogen cells by accumulation of free radicals, which mediate a whole range of classical antimicrobial mechanisms of action observed by researchers. Thus, this present study was conducted to reveal some biochemical changes regarding the antioxidant status of pathogenic microorganisms under the influence of novel chemical compounds...
Topics: antimicrobial activity, antioxidant activity, chemical compounds, copper, reference strains
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Jan 4, 2021 Veronica ESANU, Ina PALII, Veronica MOCANU, Lorina VUDU, Valeriu ESANU
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Abstract Introduction.  Pathological left ventricular (LV) remodeling in children with metabolic syndrome (MS) is associated with a significant increase in cardiometabolic risk. However, data regarding the prevalence of LV remodeling patterns in children with MS are limited. Material and methods.  An observational analytical cohort study was conducted on 145 children. The diagnosis of MS was established according to the International Diabetes Federation (IDF) criteria. We analyzed the...
Topics: metabolic syndrome, children, left ventricular remodeling, patterns
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Jan 4, 2021 Valerii USHKALOV, Aidyn SALMANOV, Liliia KALACHNIUK, Yuriy VISHOVAN, Sergiy BOIANOVSKIY, Artem USHKALOV, Andry GRANATE, Goma M. HUWIAGE, Oleksandra KEPPLE
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Abstract Introduction .  Some causative agents of sapro-zoonotic infections can multiply in the external environment (water reservoirs, soils, plants), as well as in animals, including microorganisms of the genus Yersinia. Material and methods.   Isolation and identification of Y. pseudotuberculosis was carried out in accordance with the instructions on “Epidemiology, laboratory diagnosis of yersiniosis, organization and conduct of preventive and anti-epidemiological measures”. Antibiotic...
Topics: Yersinia pseudotuberculosis, cultivation, temperature, phenotypic, traits, antibiotics, resistance,...
Abstract Introduction.  Leptospirosis is a zoonosis caused by microorganisms of the genus Leptospira with a global spread. The  main  reservoir of leptospires are the small mammals, which survive after infection, spreading the causative agent in the environment with urine. Material and methods.   The studied were conducted in 2017-2019 in different  ecosystems , where 1617 small mammals were collected, investigated for the presence of specific antibodies to Leptospira  spp . Ecological...
Topics: small mammals, Leptospira spp., leptospirosis, ecosystem, biotope
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Jan 4, 2021 Victoria BUCOV, Alexei CEBAN, Ludmila BIRCA
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Abstract Introduction . Meningococcal infection (MI) and N. meningitidis carriage are widespread. The global incidence represents a total of 500,000-1,200,000 cases per year, of which 50,000-135,000 are fatal. In European countries the incidence is 0.6-2.0 per 100,000. Infants and young people are more likely to get affected due to different genotypes of meningococci. Thus, MI surveillance is required. Material and methods.  The research purpose was to perform an epidemiological analysis of MI...
Topics: meningococcal infection, epidemiology, morbidity
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Jan 4, 2021 Nicolae FURTUNA, Alina DRUC, Octavian SAJIN, Constantin SPINU, Veaceslav GUTU, Alexei CEBAN
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Abstract Introduction.  In the Republic of Moldova, the first case of COVID-19 was confirmed on March 7, followed by a significantly increasing incidence across the country. It is important to describe the clinical and epidemiological aspects that were adjusted to the national context in order to develop and implement optimal public health care measures. Material and methods . A cross-sectional descriptive study was conducted from March 7 to April 6, 2020, using the surveillance system data of...
Topics: COVID-19, infection, Republic of Moldova, prevention, epidemiological study
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Jan 3, 2021 Vasile DUMITRAS, Sergiu CIRLAN, Andrei MARFIN, Catalina CROITORU, Elena CIOBANU
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Abstract Introduction.  Currently, there is a steadily increasing trend in losses due to flooding. Nevertheless, global warming, followed by an inevitable overuse of river valleys might further contribute to an increase in the frequency and destructive power of floods. It is quite important to trace the cause and effect chain of the economic, social and ecological impacts during the flood hazard. Material and methods.  A bibliographic research was carried out by using historical and...
Topics: flood, calamities, victims, medical management
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Jan 3, 2021 Liliana CEPOI, Ludmila RUDI, Tatiana CHIRIAC, Vera MISCU, Valeriu RUDIC
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Abstract Introduction.  As a result of increased production and spread in the environment, nanoparticles can pose a significant risk to public health. To date, the toxicity data of nanoparticles collected, using traditional models and methods, are contradictory and inconsistent. Highlighting the significant methods and markers of nanoparticle toxicity is a current research direction. Material and methods.  The strain of red microalgae Porphyridium cruentum CNM-AR-01, known as a lipid...
Topics: nanoparticles, toxicity tests, malondialdehyde, Porphyridium cruentum
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Jan 3, 2021 Yuriy VISHOVAN, Valerii USHKALOV, Oleksandra KEPPLE, Andry GRANATE
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Abstract Introduction.  Representatives of the genus Staphylococcus spp. cause a significant proportion of diseases in animals and humans. Nowadays the problem of their acquired antibiotic resistance is an urgent concern. Material and methods.  Isolation and identification of Staphylococcus spp. carried out in accordance with DSTU EN 6888:2003 standard. The  susceptibility  of the strains to antibiotics was determined by the disk diffusion method. Interpretation of the results was carried...
Topics: Staphylococcus spp., plasma coagulation, biological properties, antibiotics, susceptibility,...
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Abstract Introduction.  Many rodent species are important pests for agriculture and for urban areas. The long-eared owl is a predator that exerts constant pressure on rodent density. Material and methods . The studies were performed in winters of 2011-2013 in the cities of Chisinau and Bacau, where 599 and 82 pellets of Asio otus were collected, respectively. The prey items were identified from cranial bones extracted from pellets. Results.  Long-eared owl’s diet in both sites consists of...
Topics: Asio otus, urban environment, trophic spectrum, rodents, Microtus voles
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Jan 3, 2021 Liuba CORETCHI, Ion BAHNAREL, Mariana GÎNCU, Alexandra COJOCARI, Marcus HOFFMANN
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Abstract   Introduction.  A safe way to reduce the onset of oncological diseases is to protect the population from exposure to radon. In order to know the risk of radon influence on the health of the population, it is necessary to quantify the radon concentrations in the homes air and environment components. Material and methods.  The aim of the study was to monitor radon concentrations in the air from different types of housing (n=2500), in rural and urban areas, on the territory of the...
Topics: radon, public health, risk
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Jan 3, 2021 Stela RACOVITA, Mariana SPRINCEAN, Dumitru PONEATENCO, Eusebiu Vlad GORDUZA, Veaceslav MOSIN
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Abstract Introduction.  It is estimated that over 15% of couples of reproductive age face infertility worldwide. In about half of these cases the male factor is involved. To assess the potential of male fertility the spermiogram analysis may not always be an optimal diagnostic tool, but it remains the basic clinical tool. Material and methods.  The purpose of the study is to analyze the regional tendencies of the semen quality in male partners of couples facing infertility. A retrospective...
Topics: human semen, male infertility diagnosis, reference values
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Jan 3, 2021 Vladislav SEMERIKOV, Elena ZUBOVA, Vera LOSHKAREVA, Ludmila SOFRONOVA, Maria PERMYAKOVA
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Abstract Introduction.  Bronchopulmonary dysplasia (BPD) is the most common chronic lung disease among children of the first year of life, especially children born prematurely with extremely low and very low body weight. Material and methods.  To estimate the number of children born alive in Perm Territory between 2015 and 2017, official statistics data were used. Experimental epidemiological studies were used to assess safety, reactogenicity, immunogenic activity and preventive efficacy of...
Topics: PCV13 vaccine, pneumococcal infection, bronchopulmonary dysplasia
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Jan 3, 2021 Liliia VYGOVSKA, Vitliy NEDOSEKOV, Valerii USHKALOV, Oksana BOYKO, Oleksandra KEPPLE, Yuriy VISHOVAN, Sergiy TERESHCHENKO, Liliana DAVYDOVSKA, Sergiy BOIANOVSKIY, Valentina MOMOT, Tatyana KORCHOVA
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Abstract Introduction.  Antimicrobial resistance is a global public health problem that the world is facing today. Material and methods.  Isolation and identification of Salmonella spp. were performed according to DSTU EN 12824: 2004; DSTU ISO 18593: 2006 standards; Nutrient media were manufactured in accordance with DSTU EN ISO 11133: 2014 standard. The antibiotic susceptibility of cultures was determined by the disk diffusion method. The research findings were both studied and interpreted...
Topics: Salmonella spp., biological properties, antibiotics, resistance, susceptibility
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Jan 3, 2021 Irina RUSU, Liliana HODOROGEA, Tiberiu HOLBAN
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Abstract Introduction . Viral hepatitis C (HCV) is a significant global health problem. The risk of developing chronic HCV is up to 80% of patients, of whom 10-20% can develop liver cirrhosis or hepatocellular carcinoma which can lead to death. Treatment with direct-acting antiviral agents (DAAs) contributes to a sustained virological response (SVR) in 97-99% of cases. Material and methods.  The study was conducted on 206 patients with chronic HCV who underwent two generic antiviral agent...
Topics: chronic HCV, treatment, sofosbuvir, ledipasvir, daclatasvir, treatment, sofosbuvir, ledipasvir,...